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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K7
All Species:
15.15
Human Site:
S417
Identified Species:
30.3
UniProt:
O43318
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43318
NP_003179.1
606
67196
S417
R
G
H
R
K
T
A
S
F
G
N
I
L
D
V
Chimpanzee
Pan troglodytes
XP_001160138
472
51727
D295
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Rhesus Macaque
Macaca mulatta
XP_001099744
609
67549
S417
R
G
H
R
K
T
A
S
F
G
N
I
L
D
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62073
579
64209
A390
S
E
G
K
R
M
S
A
D
M
S
E
I
E
A
Rat
Rattus norvegicus
P0C8E4
606
67182
S417
R
G
H
R
K
T
A
S
F
G
N
I
L
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507638
595
66386
S406
R
G
H
R
K
T
A
S
F
G
N
I
L
D
V
Chicken
Gallus gallus
XP_001233491
604
67342
R407
T
A
Y
S
K
P
K
R
G
H
R
K
T
A
S
Frog
Xenopus laevis
Q7T2V3
1005
111856
V558
S
V
L
K
K
E
E
V
T
T
S
N
K
K
K
Zebra Danio
Brachydanio rerio
NP_001018586
544
61104
S366
S
S
D
S
K
R
M
S
V
E
L
S
E
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3Q6
678
75656
T400
L
T
S
S
A
E
A
T
Q
R
L
E
T
I
R
Honey Bee
Apis mellifera
XP_397248
510
58111
K333
K
I
N
N
S
S
S
K
N
N
I
S
S
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795629
463
51420
S286
S
A
K
S
A
V
K
S
H
R
R
C
N
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
99.5
N.A.
N.A.
95
99
N.A.
91.4
91.7
21.9
70.6
N.A.
34.5
41.4
N.A.
39.9
Protein Similarity:
100
75.7
99.5
N.A.
N.A.
95
99.3
N.A.
93.7
93.7
35.7
77.8
N.A.
52.2
58.7
N.A.
51.4
P-Site Identity:
100
6.6
100
N.A.
N.A.
0
100
N.A.
100
6.6
6.6
13.3
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
13.3
100
N.A.
N.A.
46.6
100
N.A.
100
13.3
20
13.3
N.A.
13.3
33.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
17
0
50
9
0
0
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% C
% Asp:
0
0
9
0
0
0
0
9
9
0
0
0
0
34
0
% D
% Glu:
0
9
0
0
0
17
9
0
9
9
0
17
9
9
9
% E
% Phe:
0
0
0
9
0
0
0
0
34
0
0
0
0
0
0
% F
% Gly:
0
34
9
0
0
9
0
0
9
34
0
0
0
0
0
% G
% His:
0
0
34
0
0
0
0
0
9
9
0
0
0
0
9
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
9
34
9
9
9
% I
% Lys:
9
0
9
17
59
0
17
9
0
0
0
9
9
9
9
% K
% Leu:
9
0
9
0
0
0
0
0
0
0
25
0
34
9
0
% L
% Met:
9
0
0
0
0
9
9
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
0
9
9
34
9
9
0
0
% N
% Pro:
0
0
0
0
9
9
0
0
0
9
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% Q
% Arg:
34
9
0
34
9
9
0
9
0
17
17
0
0
0
9
% R
% Ser:
34
9
9
34
9
9
17
50
0
0
17
17
9
17
9
% S
% Thr:
9
9
0
0
0
34
0
9
9
9
0
0
17
0
0
% T
% Val:
0
9
0
0
0
9
0
9
9
0
0
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _